Our National Cancer Center near Los Angeles is a National Cancer Institute (NCI)-Designated Comprehensive Cancer Center

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City of Hope Orange County Cancer Hospital Opening in Late 2025!

Hope is at Work in Orange County

Hiring for OC’s Only Specialty Cancer Hospital Begins Spring 2025

There are rare moments in one’s career when the chance to make a significant impact presents itself.

City of Hope Orange County is seeking the nation’s top health care professionals – from chefs to laboratory techs to nurses – to join our team as we complete the full continuum of advanced cancer research and treatment for the nation’s sixth largest county. Together, we will change the healthcare landscape for OC and beyond.

We operate the region’s largest and most advanced network of highly specialized cancer care with City of Hope Orange County Lennar Foundation Cancer Center at its center, surrounded by regional network clinics in Newport Beach, Irvine, Huntington Beach and Long Beach. Join our talent community for news and information.

Join our talent community for news and information.

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A New Cancer Hospital Takes Shape

This is the care Orange County needs today. The spectacular capstone to our 11-acre City of Hope Orange County campus is the largest new construction dedicated to cancer care in the Western United States. Slated for completion in 2025, this six-story structure will be seamlessly connected to the City of Hope Orange County Lennar Foundation Cancer Center.

Where other hospitals must serve the full spectrum of health conditions in our community, every team member at this specialty cancer hospital—from the nurses to nutritionists to physicians – will have a core focus on oncology.

Orange County Campus

The City of Hope Orange County campus is home to many of the nation’s top cancer experts and resides in the Great Park neighborhood of Irvine, Calif. It is the newest campus for City of Hope, which now brings the latest cancer clinical trials, breakthrough treatments and supportive care programs for patients and their families in five of the country’s largest metropolitan areas.

Lennar Foundation Cancer Center

Opened in 2022, OC’s most advanced cancer center delivers access to more than 800 clinical trials, leading-edge technology, and high-specialized physician-scientists. It is a place for hope and healing where the best minds can focus on ending cancer.

For Our Patients

Until now, 20% of Orange County residents were leaving the area in search of advanced cancer care. City of Hope Orange County has fulfilled a vision to bring hope closer to home.

A Top Place to Work

City of Hope Orange County has been named a Best Place to Work in the nation by Modern Healthcare and a top place to work in Orange County for three years by Orange County Business Journal. A culture of compassion, collaboration and commitment means our employee engagement scores are among the top 5% of 41,000 healthcare institutions.

Hope is at work in Orange County. There are moments in our careers that will stay with us forever. That time is now, here.

We’re calling the brightest and best to join us in our pursuit of ending cancer in this region and beyond. You can make a brighter tomorrow for your families, friends and neighbors."

Annette M. Walker, President
City of Hope Orange County

More About The Campus

We will be hiring for all roles that operate a hospital, including food services, nursing, pharmacy, lab, environment services, research, surgical services, supportive care, integrative medicine and more. Roles are also available today in locations throughout Southern California.

Lennar Foundation Cancer Center

  • 67 exam and treatment rooms
  • 15 consultation rooms
  • 53 infusion bays and rooms

Specialty Cancer Hospital

  • 73 patient beds on six floors
  • Surgical facility spanning three floors
  • Spiritual care center
  • Rehab gym

Find Us Here!

City of Hope Orange County Locations

Find expert and compassionate care through our City of Hope network, including City of Hope Orange County Lennar Foundation Cancer Center and five network locations in Sand Canyon, Newport Beach, Huntington Beach, and Long Beach. The new inpatient hospital will be located adjacent to the Lennar Cancer Center in November 2025!